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. Author manuscript; available in PMC: 2016 Jun 10.
Published in final edited form as: Crit Rev Eukaryot Gene Expr. 2016;26(1):63–96. doi: 10.1615/CritRevEukaryotGeneExpr.v26.i1.70

FIG. 16.

FIG. 16

Time-lapse AFM study of the nucleosome unwrapping process. (A) Consecutive AFM images of the nucleosome undergoing gradual unwrapping taken by time-lapse AFM. Each frame size is 200 nm. The acquisition time of one frame is ~170 seconds. (B) Arm length dependence on the frame number [reprinted with permission from the American Chemical Society, Copyright 2011].105