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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: J Immunol. 2016 May 11;196(12):4905–4914. doi: 10.4049/jimmunol.1501029

Figure 2. Association of CNS TCR with the memory/effector T cell pool.

Figure 2

CNS TCRβ sequences were compared with sequences from sorted splenic CD45RbhiCD44lo (naïve) or CD45RbloCD44hi (memory) T cells from the same mice (n=5) to determine the association of CNS-infiltrating sequences with the naïve and memory populations in the spleen. (A) Percent of unique CNS sequences that were identified exclusively in the splenic memory or naïve populations, or in both memory and naïve populations are plotted. Also plotted (far left bar), is the percent of unique CNS sequences identified anywhere within the splenic memory pool (union of percent of sequences only identified in the memory cells and identified in both memory and naïve cells). (B) Percent of total CNS sequences acquired were plotted as in (A).