Table 1.

Comparison of the antimicrobial activities of selected representative compounds of different classes of nucleoside antibiotics against selected bacterial species.^a

	Gram-positive			Gram-negative
	S. aureus	B. subtilis	M. smegmatis	E. coli	P. aeruginosa
Muraymycin A1	++	n.r.	n.r.	++/+b	+/−
Tunicamycin	−	++	−	−	−
Capuramycin	−	−	++	−	−
FR-900493	++	++	n.r.	n.r.	n.r.
Mureidomycin C	−	n.r.	n.r.	−	++
Caprazamycin B	++	++/+	++	−	++
Liposidomycin A	−	−	n.r.c	−	n.r.

^a++: good activity (MIC < 10 μg/mL), +: moderately active (10 μg/mL < MIC < 32 μg/mL), −: no notable activity (MIC > 32 μg/mL), n.r.: not reported. ^bNot active against wild-type E. coli. ^cActive against M. phlei.