TABLE 2.
[A] Comparison of patients with any EN interruption versus those without EN interruption, and [B] Comparison between patients with avoidable EN interruptions vs. those without voidable EN interruptions
| [A] EN Interruption (all) * | [B] EN Interruption (avoidable)* | |||||
|---|---|---|---|---|---|---|
| Characteristic | No (n=56) | Yes (n=24) | P-value* | No (n=65) | Yes (n=15) | P-value* |
| Age at PICU admission in years | 9.5 (2.2 – 15.3) | 1.4 (0.8 – 8.5) | 0.006 | 8.3 (2.1 – 15.2) | 1.0 (0.5 – 10.2) | 0.02 |
| Age < 1 year | 5 (9%) | 10 (42%) | 0.001 | 8 (12%) | 7 (47%) | 0.006 |
| Female gender | 24 (43%) | 16 (67%) | 0.09 | 30 (46%) | 10 (67%) | 0.25 |
| PRISM 3 score | 2.5 (0.0 – 4.0) | 3.0 (1.0 – 7.0) | 0.13 | 2.0 (0.0 – 4.0) | 3.0 (1.0 – 7.0) | 0.08 |
| Percent PRISM predicted mortality | 0.53 (0.23 – 1.11) | 1.00 (0.76 – 2.49) | 0.008 | 0.60 (0.31 – 1.21) | 1.00 (0.53 – 2.75) | 0.13 |
| PICU length of stay in days | 2.0 (1.0 – 4.0) | 18.0 (7.5 – 30.5) | <0.0001 | 2.0 (1.0 – 6.0) | 23.0 (11.0 – 69) | <0.0001 |
| Days from PICU admission to start EN | 1.0 (0.0 – 2.5) | 4.0 (2.0 – 6.5) | <0.0001 | 1.0 (0.0 – 3.0) | 5.0 (2.0 – 8.0) | 0.003 |
| EN duration in days | 1.0 (1.0 – 2.0) | 11.0 (5.0 – 16.5) | <0.0001 | 1.0 (1.0 – 3.0) | 15.0 (8.0 – 17.0) | <0.0001 |
| % PICU days given EN | 100 (50 – 100) | 57 (33 – 81) | 0.007 | 90 (46 – 100) | 58 (25 – 78) | 0.03 |
| Post-pyloric feeds | 3 (5%) | 13 (54%) | <0.0001 | 7 (11%) | 9 (60%) | 0.001 |
| Mechanical ventilation | 21 (38%) | 23 (96%) | <0.0001 | 30 (46%) | 14 (93%) | 0.001 |
| Surgery | 28 (50%) | 10 (42%) | 0.63 | 30 (46%) | 8 (53%) | 0.78 |
| PN administered | 6 (11%) | 7 (29%) | 0.05 | 7 (11%) | 6 (40%) | 0.01 |
| PN days | 5.0 (2.0 – 7.0) | 7.0 (5.0 – 12.0) | 0.40 | 7.0 (2.0 – 7.0) | 8.0 (5.0 – 12.0) | 0.49 |
| PN charge ($) | 822.50 (329.00 – 1151.50) | 1151.50 (822.50 – 1974.00) | 0.40 | 1151.50 (329.00 – 1151.50) | 1316.00 (822.50 – 1974.00) | 0.49 |
| Caloric goal reached | 28 (50%) | 21 (88%) | 0.002 | 35 (54%) | 14 (93%) | 0.007 |
| Time to reaching caloric goal in days | 1.0 (1.0 – 4.0) | 7.0 (4.0 – 11.0) | 0.0004 | 2.0 (1.0 – 6.0) | 8.0 (5.0 – 11.0) | 0.002 |
PICU (Pediatric Intensive Care Unit), PRISM (...), EN (enteral nutrition)
*
Data presented as median (inter-quartile range or n (%).
P-value from Fisher exact test or Wilcoxon rank-sum test.