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. Author manuscript; available in PMC: 2016 Jul 6.
Published in final edited form as: Sci Transl Med. 2016 Jan 6;8(320):320ra2. doi: 10.1126/scitranslmed.aad1863

Table 4. Proportion of transmissions by stage in the HIV infection and care continuum.

Infection/care stage of transmitter % of transmissions by time of diagnosis of recipient MSM (95% confidence interval)
Overall (n=617) 96/07-06/04 (n=165) 06/05-07/12 (n=145) 08/01-09/06 (n=151) 09/07-10/12 (n=156)
Undiagnosed (total) 70.9 (65.8-72.5) 67.6 (59.3-72.7) 72.3 (64.2-76.9) 71.8 (63.4-76.3) 72.2 (63.3-76.3)
     Confirmed recent infection at diagnosis 15.5 (11.9-17.4) 15 (7.6-19.4) 21.7 (15-26.5) 16.4 (11-20.8) 9.4 (5.6-14.1)
     Estimated to be in recent infection 25.1 (19.4-28.1) 17.3 (11.7-22.7) 23 (15.1-30.1) 25.9 (15.4-33.6) 34.6 (19.4-43.4)
     Estimated to be in chronic infection 30.3 (28-34) 35.2 (30.2-42) 27.6 (22.4-34) 29.5 (24.2-36.1) 28.2 (23-35.7)
Diagnosed (total) 22.4 (20.7-26.2) 23.6 (18.5-29.7) 22.9 (18.6-29.1) 22.8 (18.3-29.4) 20.7 (17.4-27.3)
     Diagnosed < 3mo, Recent infection at diagnosis 2.9 (2.2-4.1) 2.5 (1-4.9) 3.2 (1.7-5.5) 3 (1.9-5.4) 2.8 (1.8-4.4)
     No CD4 measured 1.6 (1.2-2.4) 2.9 (1.6-4.8) 0.8 (0.4-1.8) 1.5 (0.6-3) 1 (0.6-2.1)
     CD4 > 500 8.3 (7-10.3) 10.2 (6.7-14.2) 7 (4.5-10.8) 8.7 (5.9-12.5) 7.1 (5.4-10.1)
     CD4 in [350-500] 6.4 (5.4-7.9) 4.8 (2.6-7.8) 7.3 (5.1-10.5) 5.9 (4.2-8.3) 7.7 (5.7-11)
     CD4 < 350 3.4 (2.5-4.3) 3.2 (1.2-5.5) 4.6 (2.6-6.6) 3.7 (2.2-5.6) 2.1 (1.3-3.3)
ART initiated (total) 5.7 (5.2-7.8) 7 (4.8-11.7) 3.7 (2.2-6.5) 4.9 (3.7-8.1) 6.7 (5.4-10.2)
Before first viral suppression 1.8 (1.6-2.7) 2.2 (1.2-4.4) 0.7 (0.4-1.5) 1.3 (0.9-2.6) 2.8 (2.1-4.6)
After first viral suppression
     No viral load measured 0.5 (0.3-1) 0.9 (0.1-2.4) 0.1 (0-0.3) 0.3 (0.1-0.9) 0.8 (0.4-1.8)
     No viral suppression 1.4 (0.9-2.1) 2.8 (1.2-5.2) 1.2 (0.4-2.6) 0.9 (0.4-1.9) 0.5 (0.1-1)
     Viral suppression, one observation 0.4 (0.3-0.8) 0.1 (0-0.5) 0.2 (0-0.8) 0.5 (0.2-1.7) 0.6 (0.3-1.5)
     Viral suppression, >1 observations 1.6 (1.1-2.5) 1 (0.1-2.6) 1.5 (0.6-3.1) 1.9 (0.9-3.6) 2 (1.1-3.6)
Not in contact 1 (0.7-1.6) 1.8 (0.8-3.4) 1.1 (0.4-2.3) 0.5 (0.2-1.4) 0.4 (0.2-0.8)
Recent infection (total) 43.5 (36.6-46) 34.9 (25.4-40.6) 47.9 (36.9-54.8) 45.3 (33.3-54.1) 47.7 (32.8-53.8)