Supplemental Table 1.

Summary of primary Sjögren's syndrome (pSS) and Sicca patient samples uti-lized in analysis of viral profiles present in Sjögren's syndrome patient cohorts at NIH and in UK.

NIH Patient ID	Sex	Schirmer's Test	Unstimulated Saliva Flow	Focus Score (≥ 1)	Autoantibody	Diagnosis
pSS-1	Male	Negative	Low Flow	Negative	Positive	pSS
pSS-2	Female	Positive	Low Flow	Positive	Positive	pSS
pSS-3	Male	Positive	Low Flow	Positive	Positive	pSS
pSS-4	Female	Negative	Low Flow	Positive	Positive	pSS
pSS-6	Female	Positive	Low Flow	Positive	Positive	pSS
pSS-7	Male	Negative	Low Flow	Positive	Positive	pSS
pSS-9	Female	Positive	Low Flow	Negative	Positive	pSS
pSS-10	Female	Positive	Low Flow	Positive	Positive	pSS
pSS-11	Male	Positive	Normal Flow	Positive	Positive	pSS
pSS-12	Female	Positive	Low Flow	Positive	Negative	pSS
pSS-13	Female	Positive	Low Flow	Positive	Negative	pSS
pSS-14	Female	Negative	Normal Flow	Positive	Positive	pSS
pSS-15	Male	Negative	Low Flow	Positive	Positive	pSS
pSS-19	Male	Positive	Normal Flow	Positive	Positive	pSS
pSS-20	Male	Positive	Normal Flow	Positive	Positive	pSS

UK Patient ID	Sex	Schirmer's Test	Unstimulated Saliva Flow	Focus Score (≥ 1)	Autoantibody	Diagnosis
UK-1	Female	Positive	Normal Flow	Positive	Positive	pSS
UK-2	Male	Positive	Normal Flow	Positive	Positive	pSS
UK-3	Female	Positive	Low Flow	Positive	Positive	pSS
UK-4	Female	Positive	Low Flow	Positive	Positive	pSS
UK-5	Female	Positive	Low Flow	Positive	Positive	pSS
UK-6	Female	Negative	Normal Flow	Positive	Positive	pSS
UK-7	Female	Positive	Low Flow	Positive	Positive	pSS
UK-8	Female	Positive	Low Flow	Positive	Positive	pSS
UK-9	Female	Positive	Low Flow	Positive	Positive	pSS
UK-10	Female	Positive	Normal Flow	Positive	Positive	pSS
UK-11	Female	Positive	Normal Flow	Positive	Positive	pSS
UK-12	Male	Positive	Normal Flow	Positive	Positive	pSS
UK-13	Female	Positive	Low Flow	Negative	Negative	Sicca
UK-14	Female	Negative	Normal Flow	Negative	Negative	Sicca
UK-15	Female	Negative	Normal Flow	Negative	Negative	Sicca
UK-16	Female	Negative	Normal Flow	Negative	Negative	Sicca
UK-17	Female	Positive	Low Flow	Negative	Negative	Sicca
UK-18	Male	Positive	Low Flow	Negative	Negative	Sicca
UK-19	Female	Positive	Low Flow	Negative	Negative	Sicca
UK-20	Female	Negative	Normal Flow	Negative	Negative	Sicca
UK-21	Female	Positive	Normal Flow	Negative	Negative	Sicca
UK-22	Female	Positive	Normal Flow	Negative	Negative	Sicca

All pSS patients met diagnosis criteria based on the American European consensus group (AECG).