Supplemental Table 2.

Viral microarray analysis identified 9 viral probes with significantly different intensity between the collective pSS patient popu-lation compared to healthy controls.

Family Name	Probe Name	Sequence	P-value	P (Corr)	FC
Deltavirus	Deltavirus_13277517_18	GGTCAACCTCCTAAGTTCCTCTTCCTCCTCCTTGCTGAGGTTCTTTCCCCCCGCCGATAG	0.004	0.022	3.25
Herpesviridae	Herpesviridae_9629267_432	GCCCTGGGCCCCGAGGCCATCCAGGCGCGGCTGGAGGACGTGCGGATCCAGGCCCGCCGG	0.012	0.033	3.47
Astroviridae	Astroviridae_20514394_47	CAACCTCAACCTCAACCTCCTGCTCCTATTGAAGAAATACTTCTGCCTTTAGCAGAACTG	0.014	0.033	2.60
Adenoviridae	Adenoviridae_34303903_34	TTCACTAAGTTTGCCTCCAGCTCTACAAAAAATTTTAATTGAAATTTTTATTGGAAAATC	0.014	0.033	2.48
Retroviridae	Retroviridae_9629902_75	CATTGCAAGTTATTGCGATCATCTCTCTCCTCCTCGTTGGGGGGGCCAGTCAACCAGCTA	0.009	0.033	2.05
Circoviridae	Circoviridae_12280941_24	TGCCAACTTTGTAACCCCCTCCACCAACTTGGCCTATGACCCCTATATTAACTACTCCTC	0.023	0.044	2.86
Flaviviridae	Flaviviridae_157781216_244	TATACCAATGCTGTAACCTTGAACCGGAGGCCAGGAAAGTGATCTCCTCCCTCACGGAGC	0.003	0.022	-2.10
Poxviridae	Poxviridae_96980809_55	GCTTCCGCAAGGCGGTCGAGCGGCAGCTGGAGGAGGAGCAGGAGGTGAAGCTGAAGAGCC	0.003	0.022	-4.00
Poxviridae	Poxviridae_96980809_110	TCGAGCGGCAGCTGGAGGAGGAGCAGGAGGTGAAGCTGAAGAGCCTCGCGCGGCGCGAGT	0.016	0.033	-2.93

Six probes were increased in pSS compared to healthy controls and 3 probes were significantly decreased in pSS compared to healthy controls. (FC = Fold Change, P-value denotes t-test, P(Corr) denotes P < 0.05, t-test, Benjamini-Hochberg correction n = 14-15)