Supplemental Table 4.
Significant pairwise correlations identified between probes significantly increased in > 25% of the pSS patient population compared to healthy controls.
| Variable | by Variable | Correlation | Count | Lower 95% | Upper 95% | Signif Prob |
|---|---|---|---|---|---|---|
| Deltavirus_13277517_18 | Astroviridae_20514394_47 | 0.9268 | 15 | 0.7892 | 0.9758 | < 0.0001 |
| Flaviviridae_157781208_384 | Parvoviridae_51949963_15 | 0.9121 | 15 | 0.7506 | 0.9708 | < 0.0001 |
| Parvoviridae_51593836_90 | Picornaviridae_9626123_24 | 0.9097 | 15 | 0.7443 | 0.97 | < 0.0001 |
| Parvoviridae_51593836_90 | Flaviviridae_157781208_384 | 0.9056 | 15 | 0.7336 | 0.9685 | < 0.0001 |
| Flaviviridae_157781208_384 | Picornaviridae_9626123_24 | 0.8666 | 15 | 0.6373 | 0.9549 | < 0.0001 |
| Circoviridae_12280941_24 | Astroviridae_20514394_18 | 0.8614 | 15 | 0.6248 | 0.9531 | < 0.0001 |
| Parvoviridae_51593836_90 | Parvoviridae_51949963_15 | 0.8607 | 15 | 0.6231 | 0.9528 | < 0.0001 |
| Circoviridae_12280941_24 | Astroviridae_20514394_47 | 0.8038 | 15 | 0.4956 | 0.9322 | 0.0003 |
| Deltavirus_13277517_18 | Circoviridae_12280941_24 | 0.8094 | 15 | 0.5076 | 0.9343 | 0.0003 |
| Astroviridae_20514394_47 | Astroviridae_20514394_18 | 0.7947 | 15 | 0.4764 | 0.9288 | 0.0004 |
| Parvoviridae_51593836_90 | Herpesviridae_9629267_432 | 0.7615 | 15 | 0.4087 | 0.9163 | 0.001 |
| Herpesviridae_9629267_432 | Parvoviridae_51949963_15 | 0.7122 | 15 | 0.3148 | 0.8972 | 0.0029 |
| Herpesviridae_9629267_432 | Picornaviridae_157939778_31 | -0.7074 | 15 | -0.8952 | -0.306 | 0.0032 |
| Picornaviridae_9626123_24 | Parvoviridae_51949963_15 | 0.7059 | 15 | 0.3034 | 0.8947 | 0.0033 |
| Deltavirus_13277517_18 | Parvoviridae_51949963_15 | -0.6949 | 15 | -0.8903 | -0.2837 | 0.004 |
| Deltavirus_13277517_18 | Astroviridae_20514394_18 | 0.6884 | 15 | 0.2721 | 0.8877 | 0.0045 |
| Flaviviridae_157781208_384 | Deltavirus_13277517_18 | -0.6727 | 15 | -0.8813 | -0.2447 | 0.006 |
| Flaviviridae_157781208_384 | Herpesviridae_9629267_432 | 0.6656 | 15 | 0.2326 | 0.8784 | 0.0068 |
| Parvoviridae_51949963_15 | Astroviridae_20514394_47 | -0.6512 | 15 | -0.8724 | -0.2084 | 0.0086 |
| Parvoviridae_51593836_90 | Deltavirus_13277517_18 | -0.6162 | 15 | -0.8577 | -0.1519 | 0.0144 |
| Herpesviridae_9629267_432 | Picornaviridae_9626123_24 | 0.5904 | 15 | 0.112 | 0.8466 | 0.0205 |
| Flaviviridae_157781208_384 | Astroviridae_20514394_47 | -0.5871 | 15 | -0.8452 | -0.107 | 0.0214 |
| Herpesviridae_9629267_432 | Herpesviridae_126882977_334 | 0.5414 | 15 | 0.0403 | 0.8249 | 0.0371 |
| Picornaviridae_157939778_31 | Parvoviridae_51949963_15 | -0.5293 | 15 | -0.8194 | -0.0233 | 0.0425 |
| Flaviviridae_157781208_384 | Picornaviridae_157939778_31 | -0.5287 | 15 | -0.8191 | -0.0225 | 0.0428 |
| Deltavirus_13277517_18 | Picornaviridae_9626123_24 | -0.5253 | 15 | -0.8176 | -0.0179 | 0.0443 |
Significant pairwise correlations between viral probes revealed two distinct viral profiles present within the pSS patient population. (PCC, n = 15, P>0.05. Table is ranked on statistical significance of correlation.