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. 2016 Jun 10;11(6):e0157272. doi: 10.1371/journal.pone.0157272

Table 4. Comparison of the beta-cell function and insulin sensitivity between women with a normal OGTT and women with glucose intolerance postpartum.

Normal N = 76 (56.3%) Glucose intolerance N = 59 (43.7%) P value Adjusted p value
ISSI-2 index (median) 1.9(1.7–2.4) 1.6(1.2–2.1) <0.0001 0.002
Insulinogenic index/HOMA-IR index (median) 0.010(0.008–0.014) 0.009(0.005–0.015) 0.119 0.249
Matsuda index (median) 0.778(0.532–1.067) 0.656(0.386–1.224) 0.279 0.709
1/HOMA-IR index(median) 0.004(0.003–0.007) 0.004(0.002–0.009) 0.699 0.384

ISSI-2: insulin secretion sensitivity index postpartum; Insulinogenic index/HOMA-IR is a measure for beta-cell function postpartum; Matsuda: insulin sensitivity index of Matsuda postpartum; 1/HOMA-IR: the reciprocal of the homeostasis model assessment of insulin resistance post-partum; Statistical analyzes: for non-parametric variables the Mann–Whitney’s U-test were used. The p-values for the measurements post-partum are adjusted for age, BMI, ethnicity and breastfeeding. P values in bold are statistical significant.