Fig. 3.

Role of CENH3 in uniparental chromosome elimination in inter-specific hybrid embryos between H. vulgare × H. bulbosum. CENH3 (Filled circle) is loading into the centromere of H. vulgare but not of H. bulbosum, and incorporates only in the centromere of H. vulgare during the G2 phase (A). Sister chromatids of H. vulgare are separated and moved to opposite ends by attached microtubules in anaphase. However, chromosomes of H. bulbosum are abandoned, and are not inherited to daughter cells (B). As a result, chromosomes of H. bulbosum are eliminated in the inter-specific hybrid embryo.