FIG. 2.

Both patients have specific facial features. A: Patient 1: Note, squint, apparent hypertelorism, mild downslanting of the eyes, thick lips. There is prominent asymmetry of the face when attempting to smile. Note inability of the patient’s left lip to elevate. B: Patient 2: Note similar facies as older sister, together with prominent forehead and broad nose. There is less pronounced asymmetry with smiling, most notable is the failure to elevate the patient’s lip, and to partially close the eye on the right.