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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Semin Fetal Neonatal Med. 2016 Feb 18;21(3):162–173. doi: 10.1016/j.siny.2016.02.001

Table 5.

High frequency nasal ventilation (HFNV): Demographics, nasal interface, ventilator driver and settings, and effects for published studies of at least 10 infants.

Van der Hoeven Colaizy Czernik Mukerji
# infants 21 14 20 52 (79 uses)
Gestation, wk 29 (27–32) 27 (25–30) 25 (23–27) 25 (23–35)
Birth Wt, g 1010 (750–2170) 995 (438–1371) 635 (382–1020) 740 (500–2860)
Study age, d 1 (0.2–20) 30 (18–147) 31 (10–183) 20 (2–147)
Duration, hr 36 (12–108) 2 136 (7–456) 57 (1–415)
Nasal interface NP tube NP Tube NP Tube Nasal prongs/mask
Ventilator InfantStar InfantStar Leoni Plus Drager
Settings Initial
Rate: 10 Hz
Paw: 6–8 cm H2O
Amp: 24–48 cm H2O		 Initial
Rate: 10 Hz
Paw: 4–7 cm H2O
Amp: 29–60 cm H2O		 Initial
Rate: 10 Hz
Paw: 8 cm H2O
Amp: 20 cm H2O		 Varied over time
Rate: 6–14 Hz
Paw: 6–8 cm H2O
Amp: 24–48 cm H2O
Comments Success 16 (76%)
Improved ventilation
No adverse effects		 Success 13 (93%)
Improved ventilation
Short-term use only		 Success 14 (70%)
91% if 1st attempt
No adverse effects		 Success 46 (58%)
Improved ventilation
No adverse effects