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. 2016 Jun 10;6:41. doi: 10.1186/s13578-016-0108-4

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Postnatal lethality and growth retardation in Otg1 mutant mice. a Survival curves of Otg1 ^PB/PB (n = 114), Otg1 ^PB/+ (n = 208) and wild-type (n = 114) littermates. b Body weight curves of Otg1 ^PB/PB (n = 25), Otg1 ^PB/+ (n = 38) and wild-type (n = 18) littermates. c Representative image showing the body size difference between an Otg1 ^PB/PB and a wild-type mouse at P11. d Representative image of the hypodermis histological section of P4 Otg1 ^PB/PB and Otg1 ^+/+ mice, showing severe lipodystrophy of the mutant