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. 2016 Jun 10;15:68. doi: 10.1186/s12940-016-0152-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Unadjusted urinary Pb (a), Cd (b), As^IMM (c), I (d) and creatinine (e) plotted against UFR (NHANES 2009–2012 (CDC, 2015) training data). Multiple spot Cd measurements (Meharg et al., 2014) from a single volunteer are shown for comparison (f). Linear regression lines (blue) are displayed with regression slopes and r² values. *** denotes significance to p < 0.001. Point density contours were plotted using two-dimensional kernel density estimation. In (c), the transition from green to red depicts increasing concentration of urinary dimethylarsonic acid (DMA)