Table 1.
Sample Demographics Summary
| Demographic | CAMH (n = 96) | ZHH (n = 99) | PNC (n = 370) | Diff. (p)* | Combined (n = 565) |
|---|---|---|---|---|---|
| Cortical thickness analysis | |||||
| Age, mean (y) (SD) | 46 (18.8) | 33 (16) | 15 (3.6) | <.0001 | 23 (16.4) |
| Sex | 50M, 46 F | 53M, 47 F | 178M, 193 F | .58 | 281M, 286 F |
| Handedness | 89 R, 7 L | 89R, 10 L | 328 R, 42 L | .57 | 506 R, 59 L |
| IQ, mean score (SD)a | 118 (8.5)b | 106 (9.6)c | 106 (13.2)d | — | — |
| CAMH (n = 93) | ZHH (n = 99) | PNC (n = 338) | Diff. (p)* | Combined (n = 530) | |
| Fractional anisotropy analysis | |||||
| Age, mean (y) (SD) | 46 (18.7) | 32 (16) | 15 (3.5) | <.0001 | 23 (16.4) |
| Sex | 48M, 45 F | 52M, 47 F | 164M, 178 F | .66 | 264M, 270 F |
| Handedness | 87 R, 6 L | 88R, 10L, 1 NA | 303 R, 38L, 1 NA | .44 | 478 R, 54L, 2 NA |
| IQ, mean score (SD)a | 118 (8.5)e | 106 (9.6)f | 107 (13.2)g | — | — |
Note: CAMH, Centre for Addiction and Mental Health; IQ, Intelligence Quotient; NA, data not available; PNC, Philadelphia Neurodevelopmental Cohort; ZHH, Zucker Hillside Hospital. R, right handed; L, left handed; M, male; F, female.
aIQ was evaluated using different tests in each sample subset; for CAMH sample, the Wechsler Test of Adult Reading (WTAR); for ZHH, the Wide-Range Achievement Test v3 (WRAT-3); and for PNC, the Wide-Range Achievement Test v4 (WRAT-4). Therefore, no cross-sample or combined-sample statistical comparison of IQ score was performed.
IQ data were only available for a subset of each sample: b n = 85, c n = 88, d n = 370, e n = 84, f n = 87, g n = 337.
*p values for sample differences are 2 sided and were calculated using ANOVA for continuous data (age) and Fisher’s Exact Test for factor data (sex, handedness).