Table 1.

Descriptive Statistics^a for the CpG-SNP MWAS Sample, Replication Postmortem Brain Sample, and Validation Blood and Brain Samples

	Controls		Cases		All	Difference Test
	Mean	SD	Mean	SD		Statistic	P-value
CpG-SNP MWAS	N = 696		N = 712		N = 1408
Age	55.3	11.8	53.2	11.5		11.54	.001
Sex	0.46		0.45			0.19	.659
Non-nordic	0.07		0.10			3.01	.083
Replication brain	N = 27		N = 39		N = 66
Age	43.1	7.4	43.3	9.9		0.01	.909
Sex	0.70		0.59			0.47	.493
PMI	29.0	14.1	33.1	15.4		1.21	.276
pH	6.6	0.3	6.4	0.3		7.34	.009
Validation blood	N = 377		N = 370		N = 736
Age	58.4	10.4	54.7	11.0		21.87	3.5E-06
Sex	0.38		0.38			0.01	.908
Non-nordica	0.0		0.0			NA	NA

Note: MWAS, methylome-wide association studies. N indicates number of individuals. Age is given in years. Sex is coded 0 = female and 1 = male. Postmortem interval (PMI) is the time that elapsed between mortem and the collection of the biological sample. Because of screening, 0% of the validation samples have Finnish or non-Nordic Parents. Different tests are done on contingency table (chi-square test) for categorical variables and means for continuous variables (T test).

^aThis table is limited to a set of overlapping variables and supplementary table S1 provides more details in each of the samples.