Table 1.
Controls | Cases | All | Difference Test | ||||
---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Statistic | P-value | ||
CpG-SNP MWAS | N = 696 | N = 712 | N = 1408 | ||||
Age | 55.3 | 11.8 | 53.2 | 11.5 | 11.54 | .001 | |
Sex | 0.46 | 0.45 | 0.19 | .659 | |||
Non-nordic | 0.07 | 0.10 | 3.01 | .083 | |||
Replication brain | N = 27 | N = 39 | N = 66 | ||||
Age | 43.1 | 7.4 | 43.3 | 9.9 | 0.01 | .909 | |
Sex | 0.70 | 0.59 | 0.47 | .493 | |||
PMI | 29.0 | 14.1 | 33.1 | 15.4 | 1.21 | .276 | |
pH | 6.6 | 0.3 | 6.4 | 0.3 | 7.34 | .009 | |
Validation blood | N = 377 | N = 370 | N = 736 | ||||
Age | 58.4 | 10.4 | 54.7 | 11.0 | 21.87 | 3.5E-06 | |
Sex | 0.38 | 0.38 | 0.01 | .908 | |||
Non-nordica | 0.0 | 0.0 | NA | NA |
Note: MWAS, methylome-wide association studies. N indicates number of individuals. Age is given in years. Sex is coded 0 = female and 1 = male. Postmortem interval (PMI) is the time that elapsed between mortem and the collection of the biological sample. Because of screening, 0% of the validation samples have Finnish or non-Nordic Parents. Different tests are done on contingency table (chi-square test) for categorical variables and means for continuous variables (T test).
aThis table is limited to a set of overlapping variables and supplementary table S1 provides more details in each of the samples.