Figure 1.
Comparative analysis of miRNA expression levels in plasma and urine samples obtained from FSGS, MCD and control subjects. FSGS induces miRNA down-regulation in both plasma and urine. Significantly more miRNAs were down-regulated in both plasma and urine samples of FSGS patients compared to normal controls and MCD. On the other hand, miRNA expression was significantly up-regulated in both plasma and urine of MCD patients when compared to FSGS or controls. miRNAs with > 2-fold dysregulated expression are graphed for plasma and urine samples. The percentages of up- or down-regulated miRNAs are shown with corresponding up or down arrows on each graph.