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. 1979 Aug;42(8):749–752. doi: 10.1136/jnnp.42.8.749

Crossed acoustic response combined with visual and somatosensory evoked responses in the diagnosis of multiple sclerosis.

R E Clifford-Jones, G P Clarke, P Mayles
PMCID: PMC490309  PMID: 490181

Abstract

The crossed acoustic response, (CAR), a recently introduced test of brainstem function, has been studied in 66 patients with multiple sclerosis and 53 control subjects, and compared with conventional visual and somatosensory evoked responses (VER, SER). A latency abnormality was found in the CAR in 73% of patients, in the VER in 63%, and in the SER in 37%. Abnormalities have been related to the presence or absence of clinically detectable signs. All three responses detected subclinical lesions by showing abnormality in a proportion of multiple sclerosis patients who had no corresponding abnormal clinical signs (CAR 69%, VER 42%, SER 29%). The best diagnostic combination of responses was VER and CAR. Ninety per cent of patients had at least one of these two responses abnormal.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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