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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Bone. 2015 Dec 23;84:93–103. doi: 10.1016/j.bone.2015.12.052

Fig. 8.

Fig. 8

Average number of osteoclasts (NOC) per mm2 of bone surface at the bone defect area for the 7 groups at different time points is presented. Between the groups analysis revealed a higher NOC in defects treated with rhBMP-2 or LV-BMP-2 compared to OPG treated defects (groups II, II, V, and VII). No difference was seen between rhBMP-2 and LV-BMP-2. There was also no difference between the OPG treated groups. Within the group analysis showed a significant difference in the NOC at the 7- and 56-day time points compared to the 14- and 28-day time points for rhBMP-2, LV-BMP-2 and sponge alone defects. N/A: not applicable since rhBMP-2 + delOPG animals were not euthanized at days 7 or 14.