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. 2016 May 24;157:437–446. doi: 10.1007/s10549-016-3835-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — A scatterplot depicting the relation between tumour MKI67 mRNA content measured with RT-qPCR, and Ki-67 expression determined by immunohistochemistry (IHC). Vertical axis, tumour Ki-67 expression (IHC, %); horizontal axis, tumour relative MKI67 mRNA expression. The cut-off for positivity was 20 % in the Ki-67 protein assays (the horizontal line) and 34.8 in the MKI67 mRNA (qPCR) assays (the vertical line). Sections A and D depict the discordant cases, and sections B and C depict the concordant cases