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The effect of GPER-1 in reproductive system tumors.
| Cancer types | ER positive breast cancer | ER negative breast cancer | Triple negative breast cancer | Ovarian cancer | Testicular cancer | Prostate cancer |
|---|---|---|---|---|---|---|
| Proliferation | +24, 31 | +28, 31 | +40, 41 | +47, 48, 49, 50 | +55, 56, 57 | −61, 62 |
| −17, 25, 52 | −23, 36, 37 | −51, 52 | ||||
|
| ||||||
| Migration and metastasis | +18, 21, 22, 31, 15, 32 | +27, 28, 29 | +41 | +48, 49 | / | / |
|
| ||||||
| Poor survival | +20, 16 | −36 | +38, 39, 40 | +46 | / | / |
|
| ||||||
| Drug resistance | +19, 20, 21 | +26 | / | / | / | / |
