Figure 1.

CSA values in relation to functional disability and neurophysiological alterations. Higher CSA values were observed in patients with intermediate functional disability and in nerves with predominant demyelinating features, both at the lower (a, c) and at the upper (b, d) limbs. Normalized cross-sectional area (CSA^NORM) = maximal CSA of the nerve/upper threshold (UT) of the CSA normality range of the nerve (CSA^NORM = CSA^max/CSA^UT).  ^∗Significant difference (p < 0.05) versus “no/minimal impairment” (a, b) or “no/minimal alterations” (c, d).  ^†Significant difference (p < 0.05) versus “severe impairment” (a, b) or “axonal damage” (c, d). No/minimal impairment: INCAT = 0 (lower limbs) or 0-1 (upper limbs). Moderate impairment: INCAT = 1-2 (lower limbs) or 2 (upper limbs). Severe impairment: INCAT = 3–5 (lower and upper limbs).