Table 3.
No/minimal impairment (independent) |
Moderate impairment (independent/unilateral support) |
Severe impairment (bilateral support/wheelchair) |
p value | ||
---|---|---|---|---|---|
Peroneal nerve | |||||
Motor CV (m/sec) | CIDP | 40.4 ± 1.3 | 26.7 ± 14.7a | 21.0 ± 13.4 | 0.006 |
MMN | 40.7 ± 6.8 | 37.2 ± 5.5 | 33.9 ± 3.1 | 0.099 | |
| |||||
CMAP amplitude (mV) | CIDP | 4.4 ± 3.0 | 1.7 ± 1.4a | 0.1 ± 0.2 | 0.016 |
MMN | 3.1 ± 2.1 | 2.8 ± 1.8 | 1.1 ± 1.2 | 0.110 | |
| |||||
CSA popliteal fossa (mm2) | CIDP | 12.2 ± 3.1 | 17.9 ± 3.5a | 16.7 ± 2.0 | 0.045 |
MMN | 10.5 ± 1.5 | 17.3 ± 4.3 | 14.0 ± 1.9 | 0.114 | |
| |||||
CSA fibular head (mm2) | CIDP | 8.8 ± 1.7 | 11.5 ± 3.0 | 11 ± 1.3 | 0.227 |
MMN | 7.8 ± 1.5 | 10.5 ± 2.3 | 9.3 ± 2.3 | 0.112 | |
| |||||
Tibial nerve | |||||
Motor CV (m/sec) | CIDP | 39.4 ± 6.6 | 32.7 ± 12.5 | 33.9 ± 0.9 | 0.121 |
MMN | 37.4 ± 3.6 | 34.6 ± 4.5 | 35.9 ± 4.0 | 0.234 | |
| |||||
CMAP amplitude (mV) | CIDP | 3.9 ± 2.1 | 1.7 ± 2.4b | 0.3 ± 0.1 | 0.036 |
MMN | 3.8 ± 1.1 | 2.3 ± 1.3 | 2.2 ± 2.7 | 0.048 | |
| |||||
CSA popliteal fossa (mm2) | CIDP | 15.9 ± 3.8 | 26.7 ± 4.1 | 19.7 ± 3.9 | 0.037 |
MMN | 15.4 ± 3.9 | 23.8 ± 4.8 | 17.8 ± 2.2 | 0.241 | |
| |||||
CSA ankle (mm2) | CIDP | 12.6 ± 2.1 | 15.7 ± 3.8 | 11.8 ± 2.5 | 0.254 |
MMN | 12.1 ± 2.4 | 14.5 ± 3.5b | 8.7 ± 2.0 | 0.032 | |
| |||||
Sural nerve | |||||
Sensory CV (m/sec) | CIDP | 51.7 ± 3.3 | 25.1 ± 18.7 | 20.3 ± 18.3 | 0.255 |
MMN | 48.8 ± 7.8 | 45.4 ± 1.6 | 44.4 ± 4.3 | 0.441 | |
| |||||
SNAP amplitude (μV) | CIDP | 4.5 ± 2.3 | 3.4 ± 3.7 | 1.7 ± 2.9 | 0.111 |
MMN | 10.3 ± 6.1 | 9.9 ± 4.8 | 11.3 ± 5.4 | 0.638 | |
| |||||
CSA ankle (mm2) | CIDP | 3.3 ± 0.3 | 3.7 ± 0.8 | 3.3 ± 0.2 | 0.928 |
MMN | 3.0 ± 1.1 | 2.7 ± 0.4 | 2.7 ± 0.5 | 0.958 |
Results are reported as average ± standard deviation.
CMAP: compound muscle action potential.
CSA: cross-sectional area.
CV: conduction velocity.
SNAP: sensory action potential.
INCAT (inflammatory neuropathy cause and treatment) lower limbs score: no/minimal impairment = 0; moderate impairment = 1-2; severe impairment = 3–5.
aSignificant difference (p < 0.05) versus “no/minimal impairment.”
bSignificant difference (p < 0.05) versus “severe impairment.”