Table 4.
No/minimal impairment | Moderate impairment | Severe impairment | p value | ||
---|---|---|---|---|---|
Median nerve | |||||
Motor CV (m/sec) | CIDP | 39.6 ± 10.7 | 30.0 ± 14.9 | 29.5 ± 15.6 | 0.129 |
MMN | 48.9 ± 4.7 | 41.9 ± 13.9 | 40.5 ± 11.6 | 0.631 | |
| |||||
CMAP amplitude (mV) | CIDP | 6.9 ± 3.3 | 3.2 ± 2.6a | 2.2 ± 1.2 | 0.007 |
MMN | 6.7 ± 1.4 | 4.5 ± 3.3 | 3.3 ± 2.3 | 0.034 | |
| |||||
Sensory CV (m/sec) | CIDP | 34.2 ± 23.3 | 31.1 ± 23.4 | 22.4 ± 22.2 | 0.509 |
MMN | 54.5 ± 4.4 | 55.8 ± 6.2 | 58.0 ± 8.1 | 0.738 | |
| |||||
SNAP amplitude (μV) | CIDP | 15.7 ± 23.7 | 4.2 ± 4.8 | 2.5 ± 3.7 | 0.236 |
MMN | 15.9 ± 8.1 | 18.0 ± 7.3 | 18.1 ± 9.3 | 0.267 | |
| |||||
CSAmax (mm2) | CIDP | 17.8 ± 2.9 | 20.4 ± 5.7 | 14.1 ± 2.2 | 0.163 |
MMN | 12.2 ± 1.5 | 20.3 ± 4.5 | 12.8 ± 2.3 | 0.129 | |
| |||||
Intranerve variability | CIDP | 2.9 ± 2.2 | 2.8 ± 1.7 | 2.0 ± 0.7 | 0.462 |
MMN | 2.3 ± 0.6 | 2.7 ± 1.5 | 2.1 ± 1.2 | 0.263 | |
| |||||
Ulnar nerve | |||||
Motor CV (m/sec) | CIDP | 43.0 ± 12.6 | 34.3 ± 9.5 | 29.8 ± 8.7 | 0.091 |
MMN | 50.7 ± 5.0 | 39.7 ± 6.5 | 36.7 ± 7.7 | 0.099 | |
| |||||
CMAP amplitude (mV) | CIDP | 7.8 ± 2.9 | 4.6 ± 2.4a | 3.8 ± 2.4 | 0.004 |
MMN | 5.6 ± 1.9 | 4.8 ± 2.2b | 4.1 ± 3.8 | 0.045 | |
| |||||
Sensory CV (m/sec) | CIDP | 44.6 ± 17.6 | 30.8 ± 18.8 | 26.8 ± 25.6 | 0.133 |
MMN | 47.6 ± 8.9 | 51.3 ± 7.6 | 51.6 ± 8.4 | 0.688 | |
| |||||
SNAP amplitude (μV) | CIDP | 17.7 ± 10.9 | 5.5 ± 4.2 | 2.2 ± 2.5 | 0.031 |
MMN | 15.5 ± 3.6 | 14.2 ± 8.9 | 9.7 ± 9.9 | 0.256 | |
| |||||
CSAmax (mm2) | CIDP | 10.9 ± 2.9 | 14.4 ± 4.3a | 11.9 ± 2.0 | 0.038 |
MMN | 10.0 ± 2.9 | 15.2 ± 4.8 | 9.5 ± 1.5 | 0.362 | |
| |||||
Intranerve variability | CIDP | 2.4 ± 0.7 | 3.6 ± 1.2a | 2.9 ± 0.7 | 0.014 |
MMN | 2.1 ± 0.7 | 3.7 ± 1.7a | 2.2 ± 0.6 | 0.043 |
Results are reported as average ± standard deviation.
CMAP: compound muscle action potential.
CSA: cross-sectional area.
CV: conduction velocity.
SNAP: sensory action potential.
INCAT (inflammatory neuropathy cause and treatment) upper limbs score: no/minimal impairment = 0-1; moderate impairment = 2; severe impairment = 3–5.
aSignificant difference (p < 0.05) versus “no/minimal impairment.”
bSignificant difference (p < 0.05) versus “severe impairment.”