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Visualization of 2'-O-ester interferences on the (A) secondary and (B) tertiary structure of the Tetrahymena group I intron RNA. Unique interferences corresponding to the I1, I2 and fully unfolded RNA states (see Fig. 6) are colored red, blue and green, respectively. In panel B, 2'-OH groups are shown with spheres and the phosphoribose backbone as a tube. The three-dimensional structure corresponds to an extended model32 based on the crystal structure of core regions.29
