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. Author manuscript; available in PMC: 2016 Jun 12.
Published in final edited form as: Crit Care Med. 2010 Mar;38(3):871–878. doi: 10.1097/CCM.0b013e3181cdf725

Figure 5.

Figure 5

Transepithelial current (Isc) (μA/cm2) in confluent monolayers of primary rat alveolar epithelial type II cells treated for 1 hr with the TIP peptide (10 μg/mL) or the mutant TIP. The TIP or its mutant form was added in either (top) the apical or (bottom) the basolateral side of the cell monolayers. In some experiments, the cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor 172 (10 μM) or the epithelial sodium channel complex inhibitor amiloride (100 μM) was added together with the TIP. *p < .05 vs. control; **p < .005 vs. control. Data are mean ± sem; n = 3.