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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Int J Biochem Cell Biol. 2016 Apr 27;76:31–38. doi: 10.1016/j.biocel.2016.04.017

Figure 4. Inhibition of Notch signaling pathway affects the myogenic differentiation of WT and MyoD-Lkb1 myoblasts.

Figure 4

(A) MF20 (Green) and Pax7 (Red) staining showing differentiation efficiency of WT and MyoD-Lkb1 myoblasts treated with vehicle control or DAPT. Scale bars: 100 μm. (B) Inhibition of Notch signaling partially rescued the differentiation efficiency of MyoD-Lkb1 myoblasts. Different letters means P < 0.05. (C, D) The expression of differentiation related genes in WT and Myod-Lkb1 cells treated with or without DAPT. Error bars represent SEM. n=6-8.