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. 2016 Jun 13;10:158. doi: 10.3389/fncel.2016.00158

Figure 8.

Figure 8

SI alters glutamatergic transmission in DG granule cells: effect of progesterone treatment. (A) Representative traces of spontaneous excitatory postsynaptic currents (sEPSCs) recorded in voltage-clamped (−65 mV) DG granule cells of the different experimental groups. (B–D) Bar graphs summarizing the effects of SI and progesterone treatment on sEPSC amplitude (B), decay time constant (C), and frequency (D). Data are expressed as absolute values and are Mean ± SEM [n, 33 (GH), 22 (SI), 25 (GH+Prog), 19 (SI+Prog)]. (E) Representative traces of glutamatergic EPSCs evoked by paired-pulse (PP) protocol with an inter-interval of 50 ms. (F) Bar graph summarizing the averaged PP ratio of evoked EPSCs (eEPSCs) in DG granule cells from the different experimental groups. Data are Mean ± SEM [n, 15 (GH), 17 (SI), 6 (GH+Prog), 6 (SI+Prog)]. *p < 0.05; **p < 0.01 vs. GH, one-way ANOVA and Bonferroni’s post hoc test.