Table 5. Binding of rmAb to H1N1 recHA.
rmAb were screened by ELISA for reactivity with the respective recHA. Data are shown as minimum rmAb concentration (ng/ml) required to produce a 2-fold signal above negative control. “-“, no reactivity seen at concentrations ≤12.5 μg/mL.
| recHA
|
||||||
|---|---|---|---|---|---|---|
| rmAb | CA/04 (H1pdm) | CA/04 (HA1pdm) | SC/1918 (H1) | IA/1930 (H1) | Bris/59 (H1) | DE/68 (H13) |
| 065-C05 | 1.9 | 1.9 | - | - | - | - |
| 065-C11 | - | - | - | - | - | - |
| 065-D01 | 1.9 | 1.9 | 5.7 | 463 | - | - |
| 069-A09 | 1.9 | 1.9 | 51 | - | - | - |
| 069-B03 | 12500 | 12500 | - | - | - | - |
| 139-22a | 1.9 | 0.635 | 3 | - | - | - |
| 145-C09 | 1.9 | 0.57 | - | - | - | - |
| 145-D11 | 1.9 | 1.9 | - | - | - | - |
| 146-B09 | 460 | 150 | - | - | - | - |
| 146-C07 | 0.635 | 1.9 | - | - | - | - |
| 146-D11 | 0.635 | 1.9 | - | - | - | - |