Skip to main content
. 2016 Jun 13;6:27819. doi: 10.1038/srep27819

Figure 3. Glipizide inhibits tumor-induced angiogenesis, but does not affect cell proliferation in spontaneous PC.

Figure 3

(A,B) Immunohistological staining for blood vessel with CD31 was performed in the DP, VP, LP and AP lobes of the prostates. Compared with the DMSO group, the staining indicates the microvascular density is significantly decreased in the glipizide-treated mice. (C,D) Immunohistological staining against BrdU was performed on DP, VP, LP and AP lobes of the prostates. The staining indicates that glipizide exhibits no significant effect against PC cell proliferation. Bar, 50 μm. *p < 0.05, **p < 0.01.