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SCID mouse in vivo efficacy data. Mice were infected with P. falciparum Pf3D70087/N9 parasites by intravenous injection on day zero, and dosing was once daily for 4 days starting on day 3 postinfection. (A) Blood parasitemia levels were monitored daily by flow cytometry. (B) Pharmacokinetic analysis was performed after the first dose. Pharmacokinetic parameters are reported in Table S4.
