Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| DHODH IC50 (μM) |
||||
|---|---|---|---|---|
| compd | human | rat | mouse | dog |
| 1a | ∼100 | 2.6 ± 0.39 | 2.3 ± 0.64 | 16 ± 6.5 |
| 35 | >100 | >100 | >100 | >100 |
| 11 | >100 | >100 | >100 | >100 |
| 13 | >100 | >100 | >100 | >100 |
| 7 | >100 | >100 | >100 | >100 |
| 9 | >100 | >100 | >100 | >100 |
Errors represent standard deviation for four independent replicates using different batches. Each replicate IC50 was determined from triplicate data points at each concentration in the dose titration.
