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. 2016 Apr 20;7(6):558–562. doi: 10.1021/acsmedchemlett.5b00234

Table 2. Antiviral Activity of Compounds 26–42.

graphic file with name ml-2015-00234s_0004.jpg

compds R4 EC50 (μM) CC50 (μM)
26 2-Cl 0.077 >100
27 3-Cl 0.066 >100
28 4-Cl 0.058 >100
29 2-F 0.089 >100
30 3-F 0.080 >100
31 4-F 0.095 >100
32 2-CH3 0.029 >100
33 3-CH3 0.059 >100
34 4-CH3 0.142 >100
35 2-OCH3 0.056 >100
36 3-OCH3 0.098 >100
37 4-OCH3 0.679 >100
38 3-CN 0.225 >100
39 3-CF3 0.563 >100
40 3-F-4-F 0.255 >100
41 3-Cl-4-Cl 0.220 6.68
42 3-F-5-F 0.264 >100