. 2016 Apr 7;7(6):618–622. doi: 10.1021/acsmedchemlett.6b00056

Table 2. Binding Data of the Synthesized Compounds 34–38 for 5-HT₆R.

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compd	Q	R	S/D	5-HT₆K_i [nM]^a
34	7-quinolinyl	H	S	30 ± 4
35	4-isoquinolinyl	H	S	24 ± 4
36	7-quinolinyl	Me	D	82 ± 10
37	7-quinolinyl	n-propyl	D	247 ± 19
38	7-quinolinyl	n-butyl	D	219 ± 24

Mean K_i values ± SEM based on three independent binding experiments.

Table 2. Binding Data of the Synthesized Compounds 34–38 for 5-HT6R.