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| assay type | 23 | 25 | |
|---|---|---|---|
| cytochrome P450 inhibition, IC50 [μM] | 1A2 | 100 | 100 |
| 2C9 | >100 | >100 | |
| 2C19 | >100 | >100 | |
| 2D6 | >100 | >100 | |
| 3A4 | 20 | 26 | |
| solubility [mg/mL] | pH 7.4 | >5 | >5 |
| pH 2.0 | >5 | >5 | |
| microsomal stability CLint [μL/min/mg] | rat | 18 | 10 |
