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. 2016 Jun 13;6:28004. doi: 10.1038/srep28004

Table 2. The change levels of mRNAs expression encoding apoptosis, cell cycle and necessary pathways in MCF-7 cells treatment with SAHA and TRAIL.

Gene Name Description Fold change in mRNA level
SAHA TRAIL SAHA TRAIL
ABL1 NM_005157 c-abl Oncogene 1 −8.96 1.12 −9.02
DUSP6 NM_001946 Dual Specificity Phosphatase 6 115.91 8.19 178.13
EGF NM_001963 Epidermal Growth Factor 46.83 −2.47 38.18
EGR1 NM_001964 Early Growth Response 1 33.67 1.67 37.86
EPS8 NM_004447 Epidermal Growth Factor Receptor Pathway Substrate 8 7.61 1.59 7.79
FOSB NM_006732 FBJ Murine Osteosarcoma Viral Oncogene Homolog B 19.04 1.76 23.29
FASLG NM_000639 Fas Ligand 6.76 1.10 10.76
HBEGF NM_001945 Heparin-binding EGF-like Growth Factor 16.46 2.72 17.68
JUN NM_002228 Jun Proto-oncogene 14.45 2.88 19.96
LTA NM_000595 Lymphotoxin A 7.85 1.78 10.00
NFKB1 NM_003998 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cell 1 −5.94 1.77 −12.85
RHOA NM_001664 RAS Homolog Gene Family, Member A −107,493 −97,879 −79,423
TP53 NM_000546 Tumor Protein p53 −16.36 1.05 −22.29