Table 2. The change levels of mRNAs expression encoding apoptosis, cell cycle and necessary pathways in MCF-7 cells treatment with SAHA and TRAIL.
Gene Name | Description | Fold change in mRNA level |
||
---|---|---|---|---|
SAHA | TRAIL | SAHA TRAIL | ||
ABL1 NM_005157 | c-abl Oncogene 1 | −8.96 | 1.12 | −9.02 |
DUSP6 NM_001946 | Dual Specificity Phosphatase 6 | 115.91 | 8.19 | 178.13 |
EGF NM_001963 | Epidermal Growth Factor | 46.83 | −2.47 | 38.18 |
EGR1 NM_001964 | Early Growth Response 1 | 33.67 | 1.67 | 37.86 |
EPS8 NM_004447 | Epidermal Growth Factor Receptor Pathway Substrate 8 | 7.61 | 1.59 | 7.79 |
FOSB NM_006732 | FBJ Murine Osteosarcoma Viral Oncogene Homolog B | 19.04 | 1.76 | 23.29 |
FASLG NM_000639 | Fas Ligand | 6.76 | 1.10 | 10.76 |
HBEGF NM_001945 | Heparin-binding EGF-like Growth Factor | 16.46 | 2.72 | 17.68 |
JUN NM_002228 | Jun Proto-oncogene | 14.45 | 2.88 | 19.96 |
LTA NM_000595 | Lymphotoxin A | 7.85 | 1.78 | 10.00 |
NFKB1 NM_003998 | Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cell 1 | −5.94 | 1.77 | −12.85 |
RHOA NM_001664 | RAS Homolog Gene Family, Member A | −107,493 | −97,879 | −79,423 |
TP53 NM_000546 | Tumor Protein p53 | −16.36 | 1.05 | −22.29 |