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. 2016 Apr 8;30(7):2627–2636. doi: 10.1096/fj.201500179R

Figure 7.

Figure 7.

Effect of TGF-βR1 inhibitor on classic activation of monocytes and their TNF-α production in vitro. iNOS and TNF-α expressions on monocytes were suppressed by blocking TGF-βR1 A) Representative dot plots of %iNOS+ monocytes after rTGF-β, LPS/IFN-γ, and/or TGF-βR1 inhibitor treatment in vitro. B) Comparison of iNOS expression on rTGF-β, LPS/IFN-γ, and/or TGF-βR1 inhibitor-treated monocytes in vitro. C) Representative dot plots of percentage TNF-α+ monocytes after rTGF-β, LPS/IFN-γ, and/or TGF-βR1 inhibitor treatment in vitro. D) Comparison of TNF-α expression on rTGF-β, LPS/IFN-γ, and/or TGF-βR1 inhibitor-treated monocytes in vitro. Means and sem are shown; n = 3/group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.