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. 2016 Apr 8;30(7):2627–2636. doi: 10.1096/fj.201500179R

Figure 8.

Figure 8.

Effect of TGF-βR1 inhibition on inflammatory cytokine secretion from classically activated monocytes using cytometric bead array. Secretion of key inflammatory cytokines IL-12, TNF-α, and IL-6 was significantly decreased with TGF-βR1 inhibitor treatment. IL-12 (A), TNF-α (B), and IL-6 (C) secretion in cell culture supernatant from monocytes treated with rTGF-β, LPS/IFN-γ, and/or TGF-βR1 inhibitor. Means and sem are shown; n = 3/group. *P < 0.05, **P < 0.01, ****P < 0.0001.