Figure 1.

HaCaT cell migration in response to soluble or immobilized EGF. A) Displacement of the leading edge after 24 h. Different letters (a–c) indicate significant difference. P < 0.05. B) Cell speed and persistence of individual cells located on the leading edge for 24 h (lighter color indicates individual cells; darker color indicates population average). C) Wind rose plots demonstrating individual cell tracks (μm) and distribution of migration angles, where 0 indicates movement perpendicular to the leading edge; n = 75 cells for each condition. Ctrl, control; immob, immobilized; sol, soluble.