Table 1.
Clinical and hemodynamic characteristics of patients
| Characteristic | Controls (n = 3) | PAH (n = 4) | P |
|---|---|---|---|
| Male (n) | 1 | 0 | |
| Age (yr) | 64 ± 6.1 | 61 ± 5.6 | 0.65 |
| Comorbidities | |||
| Essential hypertension | 1 | 3 | |
| Dyslipidemia | 2 | 2 | |
| Systemic sclerosis | 0 | 1 | |
| Obstructive sleep apnea | 0 | 1 | |
| Fibromyalgia | 0 | 1 | |
| Depression | 0 | 1 | |
| Cervical spondylosis | 0 | 1 | |
| Unexplained dyspnea | 1 | 0 | |
| Bronchopulmonary dysplasia | 1 | 0 | |
| Tetralogy of Fallot | 1 | 0 | |
| Hemodynamics | |||
| RA pressure (mmHg) | 8.6 ± 3.1 | 9.0 ± 1.9 | 0.92 |
| PASP (mmHg) | 35 ± 6.0 | 82 ± 2.8 | <0.01 |
| PADP (mmHg) | 14 ± 3.0 | 34 ± 1.9 | <0.01 |
| mPAP (mmHg) | 23 ± 1.9 | 52 ± 1.6 | <0.0001 |
| PAWP (mmHg) | 11 ± 3.0 | 11 ± 1.2 | 0.95 |
| Cardiac output (L/min) | 6.1 ± 0.5 | 5.6 ± 0.6 | 0.58 |
| CI (L/min/m2) | 3.4 ± 0.3 | 2.7 ± 0.3 | 0.16 |
| PVR (Wood units) | 1.9 ± 0.1 | 8.7 ± 1.1 | <0.01 |
Data are presented as mean ± sem. mPAP, mean pulmonary artery pressure; PADP, pulmonary artery diastolic pressure; PAWP, pulmonary artery wedge pressure; RA, right atrial.