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. Author manuscript; available in PMC: 2016 Jun 13.
Published in final edited form as: Cell Rep. 2016 Jan 28;14(6):1477–1487. doi: 10.1016/j.celrep.2015.12.105

Figure 1. A multigenic Drosophila lung cancer model.

Figure 1

(A) Multiple UAS-containing transgenes were combined into vectors using a repeat ligation method. Up to four UAS elements were added to a single vector in the order and orientation shown. The four transgenic lines used in this study are indicated in the lower panel.

(B-C”), btl>Ras1,PTENi larvae exhibited enlarged and thickened tracheal tubes compared to btl>control larvae. Higher magnification views are shown to visualize the enlarged nuclei.