. 2015 Oct 2;36(6):1046–1058. doi: 10.1177/0271678X15606460

Table 1.

Summary of the results and statistics.

	Normoxia	Hypoxia	Absolute change	Percent change	T-test p value	Regression p value
Blood content
CaO₂ (mmol/L)	8.5±0.6	6.8±1.3	–1.7	–20.5	$< 10 - 6$ ^a
PaO₂ (kPa)	14.1± 1.4	5.3± 1.3	–8.8	–62.2	$< 10 - 6$ ^a	$< 10 - 6$ ^a
SaO₂ (%)	98.0± 0.5	78.4± 11.2	–19.6	–20.0	$< 10 - 6$ ^a	$< 10 - 6$ ^a
SvO₂ (%)	68.5±7.6	48.7±11.0	–19.9	–29.0	$< 10 - 6$ ^a	$< 10 - 6$ ^a
PaCO₂ (kPa)	5.5±0.5	4.1±0.8	–1.3	–24.3	0.002^a	0.18^a
Hemoglobin (mmol/L)	8.7±0.6	8.8±0.6	0.1	1.2	0.035^a	0.053
Glucose (mmol/L)	5. $9 \pm$ 0.6	5.4±0.4	–0.5	–8.2	$< 10 - 4$ ^a	0.014^a
Blood lactate (mmol/L)	1.0±0.2	1.0±0.4	0.05	4.9	0.38	0.089
Hemodynamics
Heart Rate (bpm)	57.0±9.0	69.0±10.2	11.9	20.9	$< 10 - 6$ ^a	$< 10 - 6$ ^a
MAP BP (mmHg)	76.6 ±8.4	75.1±8.2	–1.5	–0.02	0.17	0.024
Cerebral metabolism
CDO₂ (µmol/100 g/min)	494.3±54.7	433.2±99.8	–61.1	–12.4	0.01^a	0.73
CBF (mL/100 g/min)	58.2±6.5	67.2±22.8	9.0	15.5	0.058	$< 10 - 6$ ^a
A-V O₂ (%)	29.5±7.7	29.8 ±10.3	0.0	0.9	0.89	0.095
CMRO₂ (µmol/100 g/min)	148.9± 40.3	161.6± 53.7	12.7	8.5	0.035^a	0.004^a
NAA (mmol/L)	7.9±0.4	7.8±0.7	–0.1	–1.4	0.36	0.18
Glutamate (mmol/L)	6.4±0.4	6.7±0.5	0.3	4.7	$< 10 - 4$ ^a	0.004^a
Cerebral lactate (mmol/L)	0.4±0.2	1.2±0.3	0.8	180.3	$< 10 - 6$ ^a	$< 10 - 6$ ^a
tCr (mmol/L)	3.1 ±0.3	2.6± 0.6	–0.5	–15.2	$< 10 - 3$ ^a	0.002^a

A statistically significant change (p < 0.05).

CaO₂: arterial O₂ concentration; PaO₂: arterial O₂ pressure; SaO₂: arterial saturation; SvO₂: venous saturation; PaCO₂: arterial CO₂ pressure; MAP BP: mean arterial blood pressure; CDO₂: cerebral O₂ delivery; CBF: cerebral blood flow; A-V O₂: arteriovenous O₂ saturation difference; CMRO₂: cerebral metabolic rate of O₂; NAA: N-acetylaspartate; tCr: creatine and phosphocreatine.