Figure 3.

IP prevented the increase in integrin α_V and β₃. expression in the cerebral cortex and hippocampus of mice with global cerebral ischemia 24 hours after the ischemic event.

(A, C) Representative bands of the western blot assay for integrin α_V and β₃ protein expression, respectively. (B, D) The relative intensities of integrin α_V and β₃, respectively. β-Actin was used as an internal control. *P < 0.05, **P < 0.01, vs. sham group; #P < 0.05, vs. Isch group. Data are expressed as the mean ± SEM from six independent animals (one-way analysis of variance followed by Bonferroni post hoc analysis). The experiment was performed in triplicate. IP: Ischemic preconditioning; Isch: ischemia.