Table 2.
Clinical examinations of PAP patients.
| Patient number | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Laboratory tests | |||||||||||
| CRP (mg/L) | 3.5 | 23.3 | 9.5 | 1.0 | 4.7 | 1.0 | 21.1 | 2.7 | 1.6 | 6.5 | 5.0 |
| ESR (mm/h) | 22 | 3 | 12 | 16 | 38 | 16 | 37 | 2.0 | 2.0 | 34.0 | 25.0 |
| PaO2 (mmHg) | 62.5 | 48.5 | 75.5 | 54.3 | 59.8 | 61.2 | 63.0 | 81 | 68.8 | 62.2 | 77.4 |
| P(A-a)O2 (mmHg) | 50.6 | 140 | 21.5 | 50.8 | 48.2 | 36.8 | 42.3 | 7.9 | 34.6 | 31.7 | 41.0 |
| LDH (U/L) | 206 | 463 | 244 | 310 | 348 | 279 | 268 | 299 | 233 | 301 | 230 |
| CEA (ng/mL) | 4.0 | 13.3 | 2.3 | 5.1 | 8.2 | 41.8 | 5.6 | 45.0 | 6.0 | 6.9 | 4.0 |
| Cyfra 21-1 (ng/mL) | 7.1 | 33.8 | 6.9 | 21.6 | 12.8 | 12.7 | 13.0 | NA | NA | NA | NA |
| NSE (ng/mL) | 17.5 | 24.4 | 17.6 | 15.0 | 19.0 | 21.5 | 24.0 | 21.0 | NA | NA | NA |
| Lung function | |||||||||||
| FEV1/FVC (%) | 94.3 | 89.9 | 94.3 | 91.1 | 74.2 | 80.9 | 88.6 | 85.7 | NA | 95.4 | 100 |
| TLC (% predicted) | 65.3 | 60.4 | 71.8 | 46.4 | 54.2 | 64.2 | 78.5 | 89.6 | NA | 60.1 | 65.1 |
| FRC (% predicted) | 62.7 | 60.0 | 92.2 | 51.7 | 42.8 | 42.8 | 74.2 | 112 | NA | 37.4 | 46.4 |
| VC (% predicted) | 68.0 | 63.2 | 73.9 | 64.8 | 58.6 | 89.1 | 74.4 | 85.9 | NA | 62.5 | 88.9 |
| DLCO (% predicted) | 44.0 | 24.2 | 40.9 | 22.4 | 28.7 | 56.1 | 46.6 | 50.4 | NA | 36.5 | 41.7 |
| mMRC score | 2 | 3 | 1 | 3 | 2 | 0 | 1 | 1 | 3 | 3 | 2 |
| Diagnosis method | |||||||||||
| Surgical biopsy | + | + | − | + | + | NA | NA | NA | NA | NA | NA |
| Transbronchial biopsy | NA | NA | NA | NA | NA | − | + | NA | − | − | NA |
| BALF | + | + | + | NA | NA | + | + | + | + | + | + |
| Clinical course | R | R | SR | R | R | SR | R | R | S | R | R |
NA: not available; R: remission; SR: spontaneous remission; S: stabilization; mMRC: modified British medical research council score for shortness of breath.