Figure 2.

Key Enzymes, Regulators, and Major Intermediates in the IGS Biosynthetic Pathway.

Indole-3-yl-methyl-glucosinolate (I3G), 1MI3G, and 4MI3G are three major IGSs found in Arabidopsis. Their de novo biosynthesis is dependent on MYB34, MYB51, and MYB122, three key transcription factors that control the expression of IGS biosynthetic genes. Solid arrows indicate single enzymatic steps, whereas dashed lines stand for several enzymatic steps. IAOx is also the key intermediate leading to camalexin and auxin (adapted from Figure 8 in Frerigmann and Gigolashvili, 2014).