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. 2016 May 18;2016:7181685. doi: 10.1155/2016/7181685

Figure 4.

Figure 4

A diagram of regulatory T cell therapy in autoimmune hepatitis. Patients with autoimmune hepatitis undergo leukapheresis followed by isolation of highly pure, autologous, GMP grade, functional CD4 and CD25highCD127low regulatory T cells followed by expansion with clinical grade expander beads, IL-2, and rapamycin. These cells can be tested for their purity and stability with flow cytometry and TSDR analysis before infusing back to AIH patients.