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. 2016 Jun 7;57(7):3002–3009. doi: 10.1167/iovs.15-18555

Figure 5.

Figure 5

Inhibition of CBS/CSE does not affect hypoxia-driven angiogenic gene expression in the retinas of OIR. Mice were subjected to OIR or maintained in RA as control. Oxygen-induced retinopathy mice were injected with aminooxyacetic acid (AOAA) (IP, 3 mg/kg/day) or vehicle (Con) from P12 to P16. At P17, retinas were collected and mRNA expression of VEGF, erythropoietin (EPO), and angiopoietin-2 was analyzed by quantitative PCR (n = 6). *P < 0.001 compared with RA control; ns, not significant compared with vehicle-treated OIR mice.