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CSE deletion results in decreased neovascularization at P17. CSE+/− and CSE−/− littermates were subjected to OIR. Retinas were harvested and stained with isolectin B4 at (A) P17 and (B) P12. Representative images of retinal flat mounts are shown, and white lines outline the area of vaso-obliteration. Graph represents neovascularization and avascular area in CSE+/− and CSE−/− mice (n = 11). *P = 0.0202 compared with CSE+/−; ns, not significant.
