Table 2.

Comparison of plasma melatonin and ICAM-1 levels between the two groups

Variable	Time	Group 1	Group 2	p value
Plasma melatonin levels (pg/mL)	Preoperative	28.17 ± 12.7	3.72 ± 1.13	0.001*
	During operation	11.6 ± 4.6	2.5 ± 0.7	0.001*
	Postoperative 4 h	27.74 ± 3.49	2.38 ± 0.96	0.001*
	Postoperative 24 h	26.51 ± 10.56	19.06 ± 6.8	0.201
Plasma ICAM-1 levels (ng/mL)	Preoperative	144.7 ± 16.3	150 ± 12.13	0.20
	During operation	150.2 ± 11.6	201 ± 45.3	0.002*
	Postoperative 4 h	200 ± 40.8	270 ± 63.4	0.001*
	Postoperative 24 h	220.6 ± 60.4	240.4 ± 84.1	0.1

*Significant at p <0.05