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. 2015 Jan 30;2(1):e970048. doi: 10.4161/23723548.2014.970048

Figure 1.

Figure 1.

DYRK1A activity blocks cell cycle progression. DYRK1A is considered primarily an inhibitor of proliferation due to its capacity to either block (red lines) cell cycle promoters (green boxes), or activate (green arrows) cell cycle inhibitors (red boxes).